In addition to conducting the actual xenograft studies, the Laboratory also provides a range of supporting services, including determination of maximum tolerated dosage (MTD), acute and subacute toxicities, including:
• Dose determining studies
• Acute toxicity testing.
• Simple MTD and Step-up Step Down assays.
• Short and long-term multiple dosage studies.
• Identification of target organs.
Commercial or laboratory-developed cell lines that hardly grow subcutaneously in mice have a better chance to grow in the subrenal capsule site. We provide a complete service for establishing transplantable tumor lines from cell lines.
Subrenal capsule xenografting
Orthotopic xenografting
Subcutaneous xenografting
Necropsy
Tissue processing and paraffin block generating
Paraffin section cutting
Standard H&E staining
Standard immunohistochemistry staining
For details, please contact us by email: LTL@bccrc.ca or phone:
604-675 -8013