Dr. Colin Collins

Co-Director, Living Tumor Laboratory
Professor, Dept. of Urologic Sciences, UBC
Senior Research Scientist and Director, Laboratory for Advanced Genome Analysis, Vancouver Prostate Centre

Dr Collins is a co-Director of the Living Tumor Laboratory, a senior scientist at the Vancouver Prostate Centre and a Director of The Laboratory for Advanced Genome Analysis (LAGA). In addition, he is an associate adjunct professor at the University of California San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center and a visiting scientist at Lawrence Berkeley National Laboratory. He has held positions at Lawrence Livermore National Laboratory and Lawrence Berkeley National Laboratory at UCSF.  His current research is best described as translational genomics where mathematics, genomics, computer science, and clinical science converge in diagnostics and therapeutics.

His work as a member of the UCSF Prostate SPORE has resulted in identification of a suite of DNA based biomarkers that show promise for predicting a patient’s risk of progression and metastasis. Dr. Collins invented and patented End Sequence Profiling (ESP) the forerunner of modern paired-end sequencing. ESP is a sequence-based method for determining the physical structure, complexity, and mutation load of tumor genomes and for direct detection of fusion genes and transcripts. Dr Collins is now integrating array-based technologies and next generation sequencing technologies to radically cut costs and make very large-scale tumor genome projects and personalized oncology a reality in the near term.

Dr. Collins is on the Scientific Advisory Boards of the International Drug Discovery Science and Technology Conference (China), BIT Life Sciences Gene Conference (China), Genome British Columbia’s Molecular Lymphoma project, and Combimatrix Molecular Diagnostics. He is on the Organizing Committee of the Advances In Genome Biology and Technology (AGBT) Conference and serves on the editorial board of the Open Pathology Journal. His collaborations are extensive and global resulting in approximately 80 peer-reviewed manuscripts.  He holds multiple patents, and has received numerous awards including the California Cancer Research Programs Cornelius L. Hopper Scientific Achievement Award for Innovation.

Selected Publications:

Anna V Lapuk, Stanislav V Volik, Yuzhuo Wang, Colin C Collins. The role of mRNA splicing in prostate cancer. Asian J Androl. 2014 Jul-Aug;16(4):515-21

Fan Mo, Alexander W Wyatt, Yue Sun, Sonal Brahmbhatt, Brian J McConeghy, Chunxiao Wu, Yuzhuo Wang, Martin E Gleave, Stanislav V Volik, Colin C Collins. Systematic Identification and Characterization of RNA Editing in Prostate Tumors. PLoS One. 2014 Jul 18;9(7):e101431.

Shaylan K Govind, Amin Zia, Pablo H Hennings-Yeomans, John D Watson, Michael Fraser, Catalina Anghel, Alexander W Wyatt, Theodorus van der Kwast, Colin C Collins, John D McPherson, Robert G Bristow, Paul C Boutros. ShatterProof: operational detection and quantification of chromothripsis. BMC Bioinformatics. 2014 Mar 19;15:78

Yan Ting Chiang, Peter W Gout, Colin C Collins, Yuzhuo Wang. Prostate cancer metastasis‑driving genes: hurdles and potential approaches in their identification. Asian J Androl. 2014 Jul-Aug;16(4):545-8.

Dong Lin, Hui Xue, Yuwei Wang, Rebecca Wu, Akira Watahiki, Xin Dong, Hongwei Cheng, Alexander W Wyatt, Colin C Collins, Peter W Gout, Yuzhuo Wang. Next generation patient-derived prostate cancer enograft models. Asian J Androl. 2014 May-Jun;16(3):407-12.

Yan Ting Chiang, Kendric Wang, Ladan Fazli, Robert Z Qi, Martin E Gleave, Colin C Collins, Peter W Gout, Yuzhuo Wang. GATA2 as a potential metastasis-driving gene in prostate cancer. Oncotarget. 2014 Jan 30;5(2):451-61.

Sifeng Qu, Kendric Wang, Hui Xue, Yuwei Wang, Rebecca Wu, Chengfei Liu, Allen C. Gao, Peter W. Gout, Colin C. Collins, Yuzhuo Wang. Enhanced anticancer activity of a combination of docetaxel and Aneustat (OMN54) in a patient-derived, advanced prostate cancer tissue xenograft model. Mol Oncol. 2014 Mar;8(2):311-22.

Alexander S Brodsky, Andrew Fischer, Daniel H Miller, Souriya Vang, Shannon Maclaughlan, Hsin-Ta Wu, Jovian Yu, Margaret Steinhoff, Colin Collins, Peter J S Smith, Benjamin J Raphael, Laurent Brard.  Expression profiling of primary and metastatic ovarian tumors reveals differences indicative of aggressive disease. PLoS One. 2014 Apr 14;9(4):e94476.

Dong Lin, Alexander W Wyatt, Hui Xue, Yuwei Wang, Xin Dong, Anne Haegert, Rebecca Wu, Sonal Brahmbhatt, Fan Mo, Lina Jong, Robert H. Bell, Shawn Anderson, Antonio Hurtado-Coll,
Ladan Fazli, Manju Sharma, Himisha Beltran, Mark A Rubin, Michael E Cox, Peter W Gout, James Morris, Larry Goldenberg, Stanislav V Volik, Martin E Gleave, Colin C Collins, Yuzhuo Wang. High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development. Cancer Res, 2014 Feb 15;74(4):1272-83

M Sharma, C Levenson, R H Bell, S A Anderson, J B Hudson, C C Collins, M E Cox.  Suppression of Lipopolysaccharide-stimulated Cytokine/Chemokine Production in Skin Cells by Sandalwood Oils and Purified α-santalol and β-santalol. Phytother Res. 2014 Jun;28(6):925-32.

Charlotte Svensson, Jens Ceder, Diego Iglesias-Gato, Yin-Choy Chuan, See Tong Pang, Anders Bjartell, Roxana Merino Martinez, Laura Bott, Leszek Helczynski, David Ulmert, Yuzhuo Wang, Yuanjie Niu, Colin Collins, Amilcar Flores-Morales. REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer. Nucleic Acids Res. 2014 Jan;42(2):999-1015.

Phuong Dao, Ibrahim Numanagic, Yen-Yi Lin, Faraz Hach, Emre Karakoc, Nilgun Donmez, Colin Collins, Evan E Eichler, S Cenk Sahinalp.  Optimal Resolution of Ambiguous RNA-Seq multimappings in the Presence of Novel Isoforms. Bioinformatics. 2014 Mar 1;30(5):644-51.

Kendric Wang, Yuzhuo Wang, Colin C Collins. Chromoplexy: a new paradigm in genome remodeling and evolution. Asian J Androl. 2013 Nov;15(6):711-2.

Alan Dal Pra, Emilie Lalonde, Jenna Sykes, Fiona Warde, Adrian S Ishkanian, Alice X Meng, Chad A Malloff, John Srigley, Anthony Joshua, Gyorgy Petrovics, Theodorus van der Kwast, Andrew Evans, Michael Milosevic, Fred Saad, Colin C Collins, Jeremy A Squire, Wan L Lam, Tarek A Bismar, Paul C Boutros, Robert G Bristow. TMPRSS2-ERG Status Is Not Prognostic Following Prostate Cancer Radiotherapy: Implications for Fusion Status and DSB Repair. Clin Cancer Res. 2013 Sep 15;19(18):5202-9.

Choi SY, Collins CC, Gout PW, Wang Y. Cancer-generated lactic acid: a regulatory, immunosuppressive metabolite? J Pathol. 2013 Aug;230(4):350-5.

Alexander W Wyatt, Colin C Collins. In Brief: Chromothripsis and Cancer. J Pathol. 2013 Sep;231(1):1-3.

Alexander W Wyatt, Fan Mo, Yuzhuo Wang, Colin C Collins. The diverse heterogeneity of molecular alterations in prostate cancer identified through next-generation sequencing. Asian J Androl. 2013 May;15(3):301-8.

Souriya Vang, Hsin-Ta Wu, Andrew Fischer, Daniel H Miller, Shannon Maclaughlan, Elijah Douglass, Margaret Steinhoff, Colin Collins, Peter J S Smith, Laurent Brard, Alexander S Brodsky. Identification of Ovarian Cancer Metastatic miRNAs. PLoS One. 2013;8(3):e58226.

Chunxiao Wu, Alexander W Wyatt, Andrew McPherson, Dong Lin, Brian J McConeghy, Fan Mo, Robert Shukin, Anna V Lapuk, Steven J M Jones, Yongjun Zhao, Marco A Marra, Martin E Gleave, Stanislav V Volik, Yuzhuo Wang, S Cenk Sahinalp, Colin C Collins. Poly-gene fusion transcripts and chromothripsis in prostate cancer. Genes Chromosomes Cancer. 2012 Dec;51(12):1144-53.

Andrew McPherson, Chunxiao Wu, Alexander W Wyatt, Sohrab Shah, Colin Collins, S Cenk Sahinalp. nFuse: Discovery of complex genomic rearrangements in cancer using high-throughput sequencing. Genome Res. 2012 Nov;22(11):2250-61.

Laurie E Littlepage, Adam S Adler, Hosein Kouros-Mehr, Guiqing Huang, Jonathan Chou, Sheryl R Krig, Obi L Griffith, James E Korkola, Kun Qu, Devon A Lawson, Qing Xue, Mark D Sternlicht, Gerrit J P Dijkgraaf, Paul Yaswen, Hope S Rugo, Colleen A Sweeney, Colin C Collins, Joe W Gray, Howard Y Chang, Zena Werb. The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression. Cancer Discov. 2012 Jul;2(7):638-51.

Deniz Yorukoglu, Faraz Hach, Lucas Swanson, Colin C Collins, Inanc Birol, S Cenk Sahinalp. Dissect: detection and characterization of novel structural alterations in transcribed sequences. Bioinformatics. 2012 Jun 15;28(12):i179-87.

Anna V Lapuk, Chunxiao Wu, Alexander W Wyatt, Andrew McPherson, Brian J McConeghy, Sonal Brahmbhatt, Fan Mo, Amina Zoubeidi, Shawn Anderson, Robert H Bell, [......], Marco A Marra, Andrea Fanjul, Christopher A Maher, Arul M Chinnaiyan, Mark A Rubin, Himisha Beltran, S Cenk Sahinalp, Martin E Gleave, Stanislav V Volik, Colin C Collins. From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer. J Pathol. 2012 Jul;227(3):286-97.

Stephen Yiu Chuen Choi, Peter W Gout, Colin C Collins, Yuzhuo Wang. Epithelial immune cell-like transition (EIT): a proposed transdifferentiation process underlying immune-suppressive activity of epithelial cancers. Differentiation. 2012 Jun;83(5):293-8.

Collins CC, Volik SV, Lapuk A, Wang Y, Gout PW, Wu C, Xue H, Cheng H, Haegert A, Bell RH, Brahmbhatt S, Anderson S, Fazli L, Hurtado-Coll A, Rubin MA, Demichelis F, Beltran H, Hirst M, Marra MA, Maher CA, Chinnaiyan AM, Gleave ME, Bertino JR, Lubin M, Wang YZ. Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target. Mol Cancer Ther. 2012 Mar;11(3):775-83.

Mark Jesus M Magbanua, Eduardo V Sosa, Janet H Scott, Jeff Simko, Colin Collins, Dan Pinkel, Charles J Ryan, John W Park. Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer. BMC Cancer. 2012 Feb 28;12:78.

Chunxiao Wu, Alexander W Wyatt, Anna V Lapuk, Andrew McPherson, Brian J McConeghy, Robert H Bell, Shawn Anderson, Anne Haegert, Sonal Brahmbhatt, Robert Shukin, [......], Robert G Bristow, Steven Jm Jones, Martin Hirst, Marco A Marra, Christopher A Maher, Arul M Chinnaiyan, S Cenk Sahinalp, Martin E Gleave, Stanislav V Volik, Colin C Collins. Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer. J Pathol. 2012 May;227(1):53-61.

Fan Mo, Alexander W Wyatt, Chunxiao Wu, Anna V Lapuk, Marco A Marra, Martin E Gleave, Stanislav V Volik, Colin C Collins. Next-generation sequencing of prostate tumors provides independent evidence of xenotropic murine leukemia virus-related gammaretrovirus contamination. J Clin Microbiol. 2012 Feb;50(2):536-7.

Beltran H, Rickman DS, Park K, Chae SS, Sboner A, MacDonald TY, Wang Y, Sheikh KL, Terry S, Tagawa ST, Dhir R, Nelson JB, de la Taille A, Allory Y, Gerstein MB, Perner S, Pienta KJ, Chinnaiyan AM, Wang Y, Collins CC, Gleave ME, Demichelis F, Nanus DM, Rubin MA. Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets. Cancer Discov. 2011 Nov;1(6):487-95.

Andrew McPherson, Chunxiao Wu, Iman Hajirasouliha, Fereydoun Hormozdiari, Faraz Hach, Anna Lapuk, Stanislav Volik, Sohrab Shah, Colin Collins, S Cenk Sahinalp. Comrad: detection of expressed rearrangements by integrated analysis of RNA-Seq and low coverage genome sequence data. Bioinformatics. 2011 Jun 1;27(11):1481-8.

Anna Ritz, Pamela L Paris, Michael M Ittmann, Colin Collins, Benjamin J Raphael.  Detection of recurrent rearrangement breakpoints from copy number data. BMC Bioinformatics. 2011 Apr 21;12:114.

Aurélie Thollet, Julie A Vendrell, Léa Payen, Sandra E Ghayad, Sabrina Ben Larbi, Evelyne Grisard, Colin Collins, Marie Villedieu, Pascale A Cohen. ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells. Mol Cancer. 2010 Nov 8;9:291.

Pamela L Paris, Vivian Weinberg, Giancarlo Albo, Ritu Roy, Catherine Burke, Jeffry Simko, Peter Carroll, Colin Collins. A group of genome-based biomarkers that add to a Kattan nomogram for predicting progression in men with high-risk prostate cancer. Clin Cancer Res. 2010 Jan 1;16(1):195-202.

P L Paris, S Sridharan, A B Hittelman, Y Kobayashi, S Perner, G Huang, J Simko, P Carroll, M A Rubin, C Collins. An oncogenic role for the multiple endocrine neoplasia type 1 gene in prostate cancer. Prostate Cancer Prostatic Dis. 2009;12(2):184-91.

Ali Bashir, Stanislav Volik, Colin Collins, Vineet Bafna, Benjamin J Raphael. Evaluation of paired-end sequencing strategies for detection of genome rearrangements in cancer. PLoS Comput Biol. 2008 Apr 25;4(4):e1000051.

Benjamin J Raphael, Stanislav Volik, Peng Yu, Chunxiao Wu, Guiqing Huang, Elena V Linardopoulou, Barbara J Trask, Frederic Waldman, Joseph Costello, Kenneth J Pienta, [......], Sarah J Aerni, Raymond P Brown, Ali Bashir, Joe W Gray, Jan-Fang Cheng, Pieter de Jong, Mikhail Nefedov, Thomas Ried, Hesed M Padilla-Nash, Colin C Collins. A sequence-based survey of the complex structural organization of tumor genomes. Genome Biol. 2008;9(3):R59.

Adam Hittelman, Shivaranjani Sridharan, Ritu Roy, Jane Fridlyand, Massimo Loda, Colin Collins, Pamela L Paris. Evaluation of whole genome amplification protocols for array and oligonucleotide CGH. Diagn Mol Pathol. 2007 Dec;16(4):198-206.

Pamela L Paris, Shivaranjani Sridharan, Alicia Scheffer, Anya Tsalenko, Laurakay Bruhn, Colin Collins. High resolution oligonucleotide CGH using DNA from archived prostate tissue. Prostate. 2007 Sep 15;67(13):1447-55.

Sven Perner, Juan-Miguel Mosquera, Francesca Demichelis, Matthias D Hofer, Pamela L Paris, Jeff Simko, Colin Collins, Tarek A Bismar, Arul M Chinnaiyan, Angelo M De Marzo, Mark A Rubin. TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion. Am J Surg Pathol. 2007 Jun;31(6):882-8.

J-M Mosquera, S Perner, F Demichelis, R Kim, M D Hofer, K D Mertz, P L Paris, J Simko, C Collins, T A Bismar, A M Chinnaiyan, M A Rubin. Morphological features of TMPRSS2-ERG gene fusion prostate cancer. J Pathol. 2007 May;212(1):91-101.

Peixiang Li, Sarah Maines-Bandiera, Wen-Lin Kuo, Yinghui Guan, Yu Sun, Mark Hills, Guiqing Huang, Collin C Collins, Peter C K Leung, Joe W Gray, Nelly Auersperg. Multiple roles of the candidate oncogene ZNF217 in ovarian epithelial neoplastic progression. Int J Cancer. 2007 May 1;120(9):1863-73.

Martin Krzywinski, Ian Bosdet, Carrie Mathewson, Natasja Wye, Jay Brebner, Readman Chiu, Richard Corbett, Matthew Field, Darlene Lee, Trevor Pugh, Stas Volik, Asim Siddiqui, Steven Jones, Jacquie Schein, Collin Collins, Marco Marra. A BAC clone fingerprinting approach to the detection of human genome rearrangements. Genome Biol. 2007;8(10):R224.

Pamela L Paris, Matthias D Hofer, Giancarlo Albo, Rainer Kuefer, Juergen E Gschwend, Richard E Hautmann, Jane Fridyland, Jeffrey Simko, Peter R Carroll, Mark A Rubin, Colin Collins. Genomic profiling of hormone-naïve lymph node metastases in patients with prostate cancer. Neoplasia. 2006 Dec;8(12):1083-9.

R Roylance, P Gorman, T Papior, Y-L Wan, M Ives, J E Watson, C Collins, N Wortham, C Langford, H Fiegler, N Carter, C Gillett, P Sasieni, S Pinder, A Hanby, I Tomlinson. A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH. Oncogene. 2006 Oct 19;25(49):6544-53. Epub 2006 May 15.

Kimberly J Bussey, Koei Chin, Samir Lababidi, Mark Reimers, William C Reinhold, Wen-Lin Kuo, Fuad Gwadry, Ajay, Hosein Kouros-Mehr, Jane Fridlyand, Ajay Jain, Colin Collins, Satoshi Nishizuka, Giovanni Tonon, Anna Roschke, Kristen Gehlhaus, Ilan Kirsch, Dominic A Scudiero, Joe W Gray, John N Weinstein. Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel. Mol Cancer Ther. 2006 Apr;5(4):853-67.

Stanislav Volik, Benjamin J Raphael, Guiqing Huang, Michael R Stratton, Graham Bignel, John Murnane, John H Brebner, Krystyna Bajsarowicz, Pamela L Paris, Quanzhou Tao, David Kowbel, Anna Lapuk, Dmitri A Shagin, Irina A Shagina, Joe W Gray, Jan-Fang Cheng, Pieter J de Jong, Pavel Pevzner, Colin Collins. Decoding the fine-scale structure of a breast cancer genome and transcriptome. Genome Res. 2006 Mar;16(3):394-404. Epub 2006 Feb 3.

Guiqing Huang, Sheryl Krig, David Kowbel, Hongmei Xu, Bill Hyun, Stas Volik, Burt Feuerstein, Gordon B Mills, David Stokoe, Paul Yaswen, Colin Collins. ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction. Hum Mol Genet. 2005 Nov 1;14(21):3219-25. Epub 2005 Oct 3.

Mark van Duin, Ronald van Marion, J E Vivienne Watson, Pamela L Paris, Anna Lapuk, Nils Brown, Vanessa V Oseroff, Donna G Albertson, Daniel Pinkel, Pieter de Jong, Elizabeth P Nacheva, Winand Dinjens, Herman van Dekken, Colin Collins Cytometry A. 2005;63(1):10-9.

P L Paris, V Weinberg, J Simko, A Andaya, G Albo, M A Rubin, P R Carroll, C Collins. Preliminary evaluation of prostate cancer metastatic risk biomarkers. Int J Biol Markers. 2005 Jul-Sep;20(3):141-5.

J E Vivienne Watson, Shervin Kamkar, Karen James, David Kowbel, Armann Andaya, Pamela L Paris, Jeffry Simko, Peter Carroll, Stephanie McAlhany, David Rowley, Colin Collins. Molecular analysis of WFDC1/ps20 gene in prostate cancer. Prostate. 2004 Oct 1;61(2):192-9.

Pamela L Paris, Armann Andaya, Jane Fridlyand, Ajay N Jain, Vivian Weinberg, David Kowbel, John H Brebner, Jeff Simko, J E Vivienne Watson, Stas Volik, [......], Kees J Vissers, Fritz H Schroder, Mark F Wildhagen, Phillip G Febbo, Arul M Chinnaiyan, Kenneth J Pienta, Peter R Carroll, Mark A Rubin, Colin Collins, Herman van Dekken. Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors. Hum Mol Genet. 2004 Jul 1;13(13):1303-13.

Mark A Rubin, Sooryanarayana Varambally, Rameen Beroukhim, Scott A Tomlins, Daniel R Rhodes, Pamela L Paris, Matthias D Hofer, Martina Storz-Schweizer, Rainer Kuefer, Jonathan A Fletcher, Bae-Li Hsi, Jennifier A Byrne, Kenneth J Pienta, Colin Collins, William R Sellers, Arul M Chinnaiyan. Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer.  Cancer Res. 2004 Jun 1;64(11):3814-22.

J E Vivienne Watson, Norman A Doggett, Donna G Albertson, Armann Andaya, Arul Chinnaiyan, Herman van Dekken, David Ginzinger, Christopher Haqq, Karen James, Sherwin Kamkar, David Kowbel, Daniel Pinkel, Lars Schmitt, Jeffry P Simko, Stanislav Volik, Vivian K Weinberg, Pamela L Paris, Colin Collins. Integration of high-resolution array comparative genomic hybridization analysis of chromosome 16q with expression array data refines common regions of loss at 16q23–qter and identifies underlying candidate tumor suppressor genes in prostate cancer. Oncogene. 2004 Apr 22;23(19):3487-94.

Herman van Dekken, Pamela L Paris, Donna G Albertson, Janneke C Alers, Armann Andaya, David Kowbel, Theodorus H van der Kwast, Daniel Pinkel, Fritz H Schröder, Kees J Vissers, Mark F Wildhagen, Colin Collins. Evaluation of genetic patterns in different tumor areas of intermediate-grade prostatic adenocarcinomas by high-resolution genomic array analysis. Genes Chromosomes Cancer. 2004 Mar;39(3):249-56.

Donna G Albertson, Colin Collins, Frank McCormick, Joe W Gray. Chromosome aberrations in solid tumors. Nat Genet. 2003 Aug;34(4):369-76.

Stanislav Volik, Shaying Zhao, Koei Chin, John H Brebner, David R Herndon, Quanzhou Tao, David Kowbel, Guiqing Huang, Anna Lapuk, Wen-Lin Kuo, Gregg Magrane, Pieter De Jong, Joe W Gray, Colin Collins. End-sequence profiling: sequence-based analysis of aberrant genomes. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7696-701.

Giuseppe Zardo, Maarit I Tiirikainen, Chibo Hong, Anjan Misra, Burt G Feuerstein, Stanislav Volik, Colin C Collins, Kathleen R Lamborn, Andrew Bollen, Daniel Pinkel, Donna G Albertson, Joseph F Costello. Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors. Nat Genet. 2002 Nov;32(3):453-8.

Nisha Anand, Sabita Murthy, Gudrun Amann, Meredith Wernick, Lisa A Porter, I Howard Cukier, Colin Collins, Joe W Gray, Joachim Diebold, Doug J Demetrick, Jonathan M Lee. Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer. Nat Genet. 2002 Jul;31(3):301-5.

G Hodgson, J H Hager, S Volik, S Hariono, M Wernick, D Moore, N Nowak, D G Albertson, D Pinkel, C Collins, D Hanahan, J W Gray. Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas. Nat Genet. 2001 Dec;29(4):459-64.

C Collins, S Volik, D Kowbel, D Ginzinger, B Ylstra, T Cloutier, T Hawkins, P Predki, C Martin, M Wernick, W L Kuo, A Alberts, J W Gray. Comprehensive genome sequence analysis of a breast cancer amplicon. Genome Res. 2001 Jun;11(6):1034-42.

J W Gray, C Collins. Genome changes and gene expression in human solid tumors. Carcinogenesis. 2000 Mar;21(3):443-52.

L Shayesteh, Y Lu, W L Kuo, R Baldocchi, T Godfrey, C Collins, D Pinkel, B Powell, G B Mills, J W Gray. PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet. 1999 Jan;21(1):99-102.

C Collins, J M Rommens, D Kowbel, T Godfrey, M Tanner, S I Hwang, D Polikoff, G Nonet, J Cochran, K Myambo, [......], G B Hutchinson, J Isola, O P Kallioniemi, M Palazzolo, C Martin, C Ericsson, D Pinkel, D Albertson, W B Li, J W Gray. Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8703-8.

C Collins, J O Nehlin, J D Stubbs, D Kowbel, W L Kuo, G Parry. Mapping of a newly discovered human gene homologous to the apoptosis associated-murine mammary protein, MFG-E8, to chromosome 15q25. Genomics. 1997 Jan 1;39(1):117-8.

C Collins, K Schappert, M R Hayden. The genomic organization of a novel regulatory myosin light chain gene (MYL5) that maps to chromosome 4p16.3 and shows different patterns of expression between primates. Hum Mol Genet. 1992 Dec;1(9):727-33.

C Collins, G Hutchinson, D Kowbel, O Riess, B Weber, M R Hayden. The human beta-subunit of rod photoreceptor cGMP phosphodiesterase: complete retinal cDNA sequence and evidence for expression in brain. Genomics. 1992 Jul;13(3):698-704.

C Collins, W L Kuo, R Segraves, J Fuscoe, D Pinkel, J W Gray. Construction and characterization of plasmid libraries enriched in sequences from single human chromosomes. Genomics. 1991 Dec;11(4):997-1006.
B Weber, C Collins, C Robbins, R E Magenis, A D Delaney, J W Gray, M R Hayden. Characterization and organization of DNA sequences adjacent to the human telomere associated repeat (TTAGGG)n. Nucleic Acids Res. 1990 Jun 11;18(11):3353-61.